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# Date Author Comment
c4e891e1 14 May 2013 13:21 Eugenio Piasini

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fee31c9a 14 May 2013 13:11 Matteo Cantarelli

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3dbcc0c2 21 Sep 2012 17:17 Eugenio Piasini

Made the second apical dendrite identical to the first one.

631f457e 21 Sep 2012 15:06 Eugenio Piasini

Added two new scripts to better reproduce figure 3C in Vervaeke2012.

Koen clarified via email that the cell being tested was 210710_C1,
that the attenuation was measured over an apical dendrite (one that he
could have pathced during the experiments), and that it wasn't...

3080441e 21 Sep 2012 14:53 Eugenio Piasini

Minor: removed superfluous line.

4d768b43 20 Sep 2012 16:31 Eugenio Piasini

Minor fitting and plotting adjustments.

58ac1787 20 Sep 2012 16:30 Eugenio Piasini

Created a segment group for each of the apical dendrites in C1.

36e32302 20 Sep 2012 12:58 Eugenio Piasini

Added a (0,1) point in attenuation fit because of normalisation.

07e2707a 20 Sep 2012 12:58 Eugenio Piasini

Added a new segment group representing a single apical dendrite.

32ded58d 18 Sep 2012 17:41 Eugenio Piasini

Revert "Begun importing other version of detailed morphology GoC."

This reverts commit be055a8cbbf8955c1fc67608f7be31bddc890804.

be055a8c 18 Sep 2012 17:10 Eugenio Piasini

Begun importing other version of detailed morphology GoC.

3d50f15c 18 Sep 2012 15:41 Eugenio Piasini

Varying the number of stimulation points on the detailed dendrites.

Still fairly hard-coded, but at least I now have more than 3 points for
the exponential fit on the detailed morphology.

a1363158 14 Sep 2012 17:21 Eugenio Piasini

Removed recording of superfluous data during simulations.

c2c23cff 14 Sep 2012 16:50 Eugenio Piasini

Scripts seem to be working fine.

Attenuation seems to match between the two models
(at least with the 4-5-6 dendrite on the reduced
morphology and a specific choice of compartments
on the detailed one), but they both seem to give
different results than those in the paper.

23e72a77 14 Sep 2012 14:50 Eugenio Piasini

Tidied up the code.

ed62ce34 13 Sep 2012 16:14 Eugenio Piasini

Working on the simulation/analysis scripts.

Added plotting of dependance of maximum somatic response amplitude
on distance of stimulation along the dendritic tree.

ab253e75 13 Sep 2012 15:57 Eugenio Piasini

Leak conductance on both models has been set to 6.67e-10mSum-2,
as per supplementary information (page 3) in Vervaeke2012, where
15kOhmcm2 was reported from unpublished observations.

Also, fixed the (wrong) number of internal divisions of a segment.

e1320be9 13 Sep 2012 13:39 Eugenio Piasini

Still playing around with reduced morphology. Added an axon.

18f23cd8 12 Sep 2012 17:46 Eugenio Piasini

Playing around with morphology to see effects on FI and attenuation.

575383cc 12 Sep 2012 16:13 Eugenio Piasini

Adjusted spike detection threshold to avoid picking up doublets
in the Vervaeke cell when calculating the F-I curve.

f920ef97 12 Sep 2012 15:42 Eugenio Piasini

Added scripts for simulating and plotting an F-I curve comparison.

9b116d9d 12 Sep 2012 13:38 Eugenio Piasini

Integrating fast segment-to-soma distance calculation in nC
allows to meaningfully compare dendritic attenuation effects
on different (and complex) morphologies.

dce3c5dd 12 Sep 2012 13:34 Eugenio Piasini

Fixed a remaining issue with the detailed morphology cell.

Note that I turned off again all Na channels.

Now pure NeuroML morphology read/write seems to be working fine,
except that it removes property elements tagged 'comment'.
This will need to be fixed in neuroConstruct, but doesn't have...

7a50584e 12 Sep 2012 11:28 Eugenio Piasini

Reverted morphologically-detailed cell model back to its original form
to fix some issues (namely, loss of 'number of internal divisions'
properties) generated when doing NeuroML write/read with older versions
of neuroConstruct.

cc5e5cec 12 Sep 2012 11:12 Eugenio Piasini

Modified leak conductance to match what Koen did.

f878dab0 11 Sep 2012 13:38 Eugenio Piasini

Comparing attenuation in the original (Koen's) model and in my reduced one.

Important: to get to a meaningful comparison,
I'm tweaking the spatial discretisation of the original model.

4778e23f 11 Sep 2012 12:11 Eugenio Piasini

Simulating attenuation for original Golgi model (Na channels switched off as per TTX)

69070de1 11 Sep 2012 10:26 Eugenio Piasini

Added a new simulation configuration where GJGolgi_Reduced is simply left alone.

705f351b 10 Sep 2012 17:09 Eugenio Piasini

Actual reference morphologies.

9b9e2cfb 10 Sep 2012 15:08 Eugenio Piasini

Committing reference morphologies, now that neuroConstruct has been fixed to
not shuffle channels and synaptic types in NeuroML serialisations and to
keep track of the number of internal divisions in each segment. See r1686
and r1689 in nC's svn repo.

856b0a7f 06 Sep 2012 17:21 Eugenio Piasini

Now the location of the synaptic input can be changed, and can be iterated over. Also added a simple plotting script.

7860329c 05 Sep 2012 18:32 Eugenio Piasini

Trying to script an attenuation-length analysis that could be compared
to Koen's 2012 paper.

The script itself is not yet usable. I have imported a cell from
Vervaeke2012 (mainly for the synaptic model, but also to keep it there
as a comparison) and a spike relay that I need to simulate a single...

10895128 03 Sep 2012 12:27 Eugenio Piasini

Initial commit: nC project.

39386d82 03 Sep 2012 12:26 Eugenio Piasini

Initial commit: ignore file.