Primary Auditory Cortex network (The ACnet2 model)

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This combined source code distribution and tutorial for the ACnet2 model gives instructions for reproducing the simulation results shown in Figure 1 of:

[Beeman D (2013) A modeling study of cortical waves in primary auditory cortex. BMC Neuroscience, 14(Suppl 1):P23 doi:10.1186/1471-2202-14-S1-P23.](http://www.biomedcentral.com/1471-2202/14/S1/P23)

![](https://raw.github.com/OpenSourceBrain/ACnet2/master/GENESIS/C0003Aasc_prop-sm.png)

Full details of this network model of layer IV of the primary auditory cortex are contained in the tutorial/documentation for the ACnet2 GENESIS model: see [[ACnet2-docs]]. There is also a poster presentation of this work from CNS 2013 (see [here](https://github.com/OpenSourceBrain/ACnet2/raw/master/GENESIS/figures/Beeman-CNS2013-poster-bottom.pdf) and [here](https://github.com/OpenSourceBrain/ACnet2/raw/master/GENESIS/figures/Beeman-CNS2013-poster-top.pdf)).

In addition to their scientific purpose, these simulation scripts were developed as a tutorial example for the construction of realistic cortical networks. The simulation scripts are designed to be run with GENESIS 2.3 and are extensively commented, are easily customizable and are designed for extension to more detailed models, or conversion to other simulation systems. The model is slowly being implemented in GENESIS 3 (G-3) and a conversion to [neuroConstruct](http://www.neuroconstruct.org) is [in development](https://github.com/OpenSourceBrain/ACnet2/tree/master/neuroConstruct).

The scripts will be of particular interest to those GENESIS network modelers who have not taken advantage of the ten-fold speed increase available with the use of ‘hsolve’ for network simulations.

This package also contains both GENESIS and simulator-independent [Python tools for the visualization and analysis of network activity](https://github.com/OpenSourceBrain/ACnet2/tree/master/GENESIS/Gpython-tools).

[[ACnet2-docs]] suggests experiments that may be tried with the many configurable options in the scripts, and ways to extend the model. It is my hope that this short tutorial and the example simulation scripts can provide a head start for a graduate student or postdoc who is beginning a cortical modeling project.

I encourage you to extend and share this tutorial/documentation and simulation script package with others. The files here may be freely

distributed under the terms of the [GNU Lesser General Public License version 2.1](https://github.com/OpenSourceBrain/ACnet2/blob/master/GENESIS/figures/copying.txt).

[David Beeman](/users/46)

University of Colorado, Boulder

dbeeman@colorado.edu

Sat Aug 31 12:30:34 MDT 2013