L5 Pyramidal Neuron Almog and Korngreen (2014)¶

Model description¶

This model originally appeared in *Almog M, Korngreen A (2014)* A Quantitative Description of Dendritic Conductances and Its Application to Dendritic Excitation in Layer 5 Pyramidal Neurons J Neurosci 34(1):1.

The relevant neuron files can be downloaded from modelDB.

Conversion to NeuroML¶

We are currently (as of Jan/2014) converting the original model to NeuroML. Most .mod mechanisms can be mapped to ChannelML with exception of the Calcium mechanisms described in terms of the GHK formalism. These latter needed to be translated to NeuroML2, which supports arbitrary current laws.

NeuroConstruct project¶

Ion Mechanisms¶

Both original (.mod) and NeuroML versions of the ionic mechanisms were imported into a neuroConstruct project, with simulation configurations allowing the comparison of both implementations. Mechanisms were named according the following convention: the original .mod_ mechanisms were suffixed with *nrn, while the NeuroML mechanisms had no suffix.

h4. Morphology
Cell morphology from the*modelDB_ project was exported to NeuroML using neuron.

Idiosyncrasies in the conversion¶