Wiki » History » Version 6
Padraig Gleeson, 30 Apr 2014 14:57
1 | 1 | Padraig Gleeson | Introduction to using the Traub et al 2005 model |
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2 | 1 | Padraig Gleeson | ================================================ |
3 | 1 | Padraig Gleeson | |
4 | 4 | Padraig Gleeson | First, and most importantly, please remember that this is a **work in progress**! |
5 | 1 | Padraig Gleeson | |
6 | 6 | Padraig Gleeson | The original Traub et al model was developed in FORTRAN, this was converted to NEURON by Tom Morse and Michael Hines (for important information on this see [here](http://senselab.med.yale.edu/ModelDB/ShowModel.asp?model=82894&file=\nrntraub\README)), and this has now been converted to NeuroML & neuroConstruct. |
7 | 4 | Padraig Gleeson | |
8 | 1 | Padraig Gleeson | Install neuroConstruct & get latest project |
9 | 2 | Padraig Gleeson | ------------------------------------------- |
10 | 1 | Padraig Gleeson | |
11 | 1 | Padraig Gleeson | See the instructions [here](http://www.opensourcebrain.org:8080/projects/neuroconstructprojects/wiki/Wiki) regarding obtaining the latest version of neuroConstruct. |
12 | 4 | Padraig Gleeson | |
13 | 4 | Padraig Gleeson | Install NEURON, GENESIS or MOOSE (see project:simulators). |
14 | 4 | Padraig Gleeson | |
15 | 4 | Padraig Gleeson | To get a local copy of the Thalamocortical project type: |
16 | 4 | Padraig Gleeson | |
17 | 6 | Padraig Gleeson | `git clone git://github.com/OpenSourceBrain/Thalamocortical.git` |
18 | 4 | Padraig Gleeson | |
19 | 4 | Padraig Gleeson | View a cell in 3D |
20 | 4 | Padraig Gleeson | ----------------- |
21 | 4 | Padraig Gleeson | |
22 | 5 | Padraig Gleeson | Open neuroConstruct and view a cell in 3D… |
23 | 1 | Padraig Gleeson | |
24 | 5 | Padraig Gleeson | More… |
25 | 5 | Padraig Gleeson | |
26 | 4 | Padraig Gleeson | Test installation with single cell simulation |
27 | 1 | Padraig Gleeson | --------------------------------------------- |
28 | 4 | Padraig Gleeson | |
29 | 5 | Padraig Gleeson | Run a single cell on NEURON… |
30 | 1 | Padraig Gleeson | |
31 | 5 | Padraig Gleeson | More… |
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33 | 1 | Padraig Gleeson | Generate synapse files |
34 | 1 | Padraig Gleeson | ---------------------- |
35 | 1 | Padraig Gleeson | |
36 | 5 | Padraig Gleeson | Currently the majority of the synapse models (ChannelML based synapses in **cellMechanism** folder) are not included in the project in the repository. |
37 | 5 | Padraig Gleeson | |
38 | 5 | Padraig Gleeson | These are generated by a script **makeSyns.sh** in **pythonScripts/netbuild**. This script was manually created from the info in teh Appendix of the original paper (it’s easier to check/update the values in **makeSyns.sh** than through the neuroConstruct GUI). |
39 | 5 | Padraig Gleeson | |
40 | 5 | Padraig Gleeson | This script (or **makeSyns.bat** on Windows) needs to be run once to generate files **cellMechanisms/Syn\_AMPA\_L4SS\_L4SS/ChannelMLSyn.xml** etc. |