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Padraig Gleeson, 30 Apr 2014 14:57

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Introduction to using the Traub et al 2005 model
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First, and most importantly, please remember that this is a **work in progress**!
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The original Traub et al model was developed in FORTRAN, this was converted to NEURON by Tom Morse and Michael Hines (for important information on this see [here](http://senselab.med.yale.edu/ModelDB/ShowModel.asp?model=82894&file=\nrntraub\README)), and this has now been converted to NeuroML & neuroConstruct.
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Install neuroConstruct & get latest project
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See the instructions [here](http://www.opensourcebrain.org/projects/neuroconstructprojects/wiki/Wiki) regarding obtaining the latest version of neuroConstruct.
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Install NEURON, GENESIS or MOOSE (see project:simulators).
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To get a local copy of the Thalamocortical project type:
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`git clone git://github.com/OpenSourceBrain/Thalamocortical.git`
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View a cell in 3D
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Open neuroConstruct and view a cell in 3D…
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More…
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Test installation with single cell simulation
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Run a single cell on NEURON…
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More…
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![](Thalamocortical_067.png)
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Generate synapse files
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Currently the majority of the synapse models (ChannelML based synapses in **cellMechanism** folder) are not included in the project in the repository.
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These are generated by a script **makeSyns.sh** in **pythonScripts/netbuild**. This script was manually created from the info in teh Appendix of the original paper (it’s easier to check/update the values in **makeSyns.sh** than through the neuroConstruct GUI).
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This script (or **makeSyns.bat** on Windows) needs to be run once to generate files **cellMechanisms/Syn\_AMPA\_L4SS\_L4SS/ChannelMLSyn.xml** etc.