Network models of V1

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Ramon Martinez, 26 Jun 2014 09:36


Network models of V1

This project will be used to test implementations in PyNN (and eventually NeuroML) of published models of primary visual cortex (V1) based on spiking point neurons.

An initial focus will be on Lauritzen and Miller, 2003, but other models investigated will include Ozeki et al., 2009 and Sadagopan and Ferster, 2012.

This project is part of the INCF Google Summer of Code 2014.

Troyer Model

Here I will describe breifly the implementation of Troyer et al (1998).

In order to run this model is necessary to first install git and PyNN and the appropriate simulator.

After that you can clone directly from git using:

git clone https://github.com/OpenSourceBrain/V1NetworkModels.git

As the project stands at this moment the workflow can be described in two steps. First there is a script produces_lgn_spikes.py that creates the spike train for the cells in the Lateral Geniculate Nucleus (LGN). After the spikes are created they are stores in pickled format along with their respective positions to identify them downstream in the worflow. After we have the spikes train the file lgn.py uses the PyNN's SpikeSourceArray to create an LGN array with the spikes that we have produced in the other file. Using the stored positions we can, in the same file, create the thalamo-cortical connectivity using a Gabor-like sampling mechanism. The next step is to create the cortical-cortical connections with the correlations between cortical cells' receptive fields.

Bibliography

Lauritzen TZ and Miller KD, Different roles for simple-cell and complex-cell inhibition in V1. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, 23(32): 10201-13
Ozeki H, Finn IM, Schaffer ES, Miller KD and Ferster D, Inhibitory stabilization of the cortical network underlies visual surround suppression. Neuron, 2009, 62(4): 578-92
Sadagopan S and Ferster D, Feedforward origins of response variability underlying contrast invariant orientation tuning in cat visual cortex. Neuron, 2012, 74(5): 911-23