Neocortical modelling

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Padraig Gleeson, 30 Apr 2014 14:57


Neocortical models in the Open Source Brain repository

Cellular models

There are a number of detailed cell models from the neocortex in OSB.

Generic cortical pyramidal cell

Minimal HH models - Pospischil et al. 2008 (single compartment, conductance based; Regular Spiking (RS) neurons & Intrinsically Bursting (IB) neurons)
Primary Auditory Cortex network is a network model of the thalamorecipient layer (IV) of primary auditory cortex (AI), and consists of 2 populations, pyramidal cells and basket cell interneurons.
Piriform Cortex Pyramidal Neuron

Layer 2/3 Pyramidal cell

Thalamocortical network - Traub et al. 2005 (Fast Regular Bursting & Regular Spiking)

Layer 4 Spiny Stellate cell

Thalamocortical network - Traub et al. 2005

Layer 5 Pyramidal cell

L5 Pyramidal Cell - Mainen et al. 1995:
L5 Pyramidal cell - Rothman et al. 2009
Thalamocortical network - Traub et al. 2005 (Intrinsically bursting & Regular Spiking)
Layer 5b Pyramidal cell - Hay et al. 2011

There is a *dedicated page on modelling L5 cells here.

Layer 6 Pyramidal cell

Thalamocortical network - Traub et al. 2005

Interneurons

Thalamocortical network - Traub et al. 2005 (Superficial & Deep Basket, Axo-axonic & LTS interneurons)
Primary Auditory Cortex network is a network model of the thalamorecipient layer (IV) of primary auditory cortex (AI), and consists of 2 populations, pyramidal cells and basket cell interneurons.
Minimal HH models - Pospischil et al. 2008 (Fast Spiking (FS) neurons)

Network models

Abstract cortical networks

Izhikevich Spiking Neuron Model
Balanced network with inhibitory plasticity - Vogels et al. 2011
Self Sustained Network Activity - Destexhe 2009
Sparsely connected spiking neuron network - Brunel 2000

Thalamocortical networks

Thalamocortical network - Traub et al. 2005

See the page on Modelling the thalamocortical loop