L5 Pyramidal cell - Rothman et al. 2009
OSB endorsed project
Curation against published models
Rothmanetal koleetal pyrcell Rothmanetal koleetal pyrcell Rothmanetal koleetal pyrcell

Description


A project which was used in Rothman et al. “Synaptic depression enables neuronal gain control” Nature 2009 to demonstrate gain control in realistic cell models. Based on cell model from Kole et al. 2008 (obtained from http://senselab.med.yale.edu/modeldb/ShowModel.asp?model=114394).

Status

Rothman et al 2009 used cell in neuroConstruct with original mod files (File based cell mechanisms). Channels converted to ChannelML, but full cell needs further testing in NeuroML/GENESIS/MOOSE.

NeuroML v1.x support
NEURON support
GENESIS 2 support
MOOSE support

Members

Developer: Padraig Gleeson

Scientific Coordinator: Jason Rothman

References

The original published version of this model is available on ModelDB

This model was originally developed in: NEURON

The code for this model is hosted on GitHub: https://github.com/OpenSourceBrain/RothmanEtAl_KoleEtAl_PyrCell